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Moonshots · 3 min · Nov 11, 2026
Vertical integration can unblock automation across supply chains
Emad suggests pairing open-source models with Anthropic access to build hardware; Salim Ismail recounts an automated logistics system stalled by company silos.
In this episode
Full analysis- 43:18Longer AI work horizons could shift companies toward outcome delegation8 min
- 53:52Treating gene therapy as an approved platform could lower costs5 min
- 1:49:42Robotics startups should target valuable problems, not easy onesPro pick 6 min
- 39:59AI agents can steer users toward more token spending3 min
- 20:20AI could overtake human output per kilowatt-hour by 20272 min
- 1:14:50Vertical integration can unblock automation across supply chains3 min
- 36:14Anthropic may generate media by treating each modality as code3 min
- 1:39:11AI-run companies may begin as state-level legal experiments6 min
“And what Elon has done in recognizing this has gone, well, the hell with the supply chain. We need to own our own supply chain.”
Salim Ismailat 1:16:50 · MoonshotsTakeaways
- A full automated logistics workflow stalled at company handoffs.
- Separate loading and sorting teams blocked deployment.
- Salim points to owning the supply chain as a way forward.
About this segment
Emad suggests pairing open-source models with Anthropic access to build hardware; Salim Ismail recounts an automated logistics system stalled by company silos. He argues owning the supply chain lets a company capture gains across steps.
Chairman, OpenExO
Co-wrote Exponential Organizations; was Singularity University's founding executive director; sold Ångströ to Google.

Peter Diamandis, Host · Founder, XPRIZE
Co-founded Singularity University and founded Zero-G; co-wrote the books Abundance and Bold.

Dave Blundin, Host · Founder & GP, Link Ventures
Has co-founded 23 companies; founding CEO of Vestmark and chairman of insurance marketplace EverQuote.

Alexander Wissner-Gross, Host · Founder, Reified
Has backed and advised 40+ tech companies, directly and through 021T Capital and Reified; writes The Innermost Loop.
From “Jensen’s Spy Probe, Anthropic’s Debut Week, and Elon’s 30M Robot Workforce | #310”, Nov 11, 2026. Watch the full episode
Thanks. We'll look at and fix what's off.
Transcript
Transcribed by machine (Whisper) from the episode’s audio, so a word may be off here and there.
- 1:14:56
oh i'm thinking about this and i'm like there's clearly a massive of need for open source and internals and spacex can win that he should just open source all his models and then he should do a deal with anthropic that he gets their models at cost basically and he should use that to build better physics hardware and just out compete everyone on chips and hardware like why does he need to build the craziest models if he has unlimited deployment capability of anthropics models on the frontier and why does he need to compete with them when he can have a tesla power wall with a gpu in every company in america you know like he should have that dual strategy instead for the frontier use it to build better machines get it at cost from from a um anthropic and on the other side own the open source ai because that's the stuff that
- 1:15:50
actually matters for society which is what he cares about you know and he can win well let's Let's move to the hardware side. Wait, wait, wait, wait. I want to make a couple of points. I think one warning, right? These are like, this is the target, not capacity, right? Because this is, we're kind of hoping that we can get there. We're ways away from getting there yet. You're saying on the chip manufacturing?
- 1:16:13
On the chip manufacturing, sorry. We're quite a ways away from the scale that he's talking about. But that's, the directionality is absolutely right. But there's something else here that's really important that I've kind of been running up against a lot with companies lately, which is, you know, I was at a earlier this year, I was at the MODX supply chain conference, and somebody built a complete end-to-end logistics thing where a truck would pull up, a robot would unload the truck, load it up, take it over, and then you'd have a stock-picking robot loading up totes, and then it would get dispatched, et cetera.
- 1:16:44
I was like, this is amazing. This kind of solves a huge chunk of supply chain. How's it going? And they're like, terrible, because each company has their loading, department, their sorting department, and they can't get it into the companies. And what Elon has done in recognizing this has gone, well, the hell with the supply chain. We need to own our own supply chain. So you get all the exponentials across the board.
- 1:17:05
And the vertical integration is going to become more and more critical for companies going forward. That's always been his game, right? And Dave and I were at Figure yesterday recording a pod that will be coming out, I think, after this pod. And that's Brett's game, too, vertically integrate everywhere. Oh, my God. Brett is such an Elon. holy crap yeah did you ask about the multiple hands did you ask about the multiple hands oh my god it goes so far beyond so far Salim, you've got to see what he's doing.